The nitric oxide-independent soluble guanylate cyclase activator ataciguat continued to show promise for slowing the progression of fibrocalcific aortic valve stenosis in phase I and II studies.

DAVID MONTGOMERY: Aortic stenosis is a tightening of one of the four major valves of the heart. The aortic valve is particularly important because the aortic valve is the gateway to the rest of ...

Aortic stenosis (AS) occurs when the orifice of the aortic valve is significantly reduced due to the failure of the aortic valve leaflets to open fully during systole. This causes an effective ...

Auscultation of the heart in patients with aortic stenosis can be very helpful in both the diagnosis and determining the severity of disease. The typical murmur of aortic stenosis is a high ...

Are you searching for effective medications to treat 'Aortic Valve Stenosis'? This comprehensive guide provides the latest information on medications-both generic and branded-that are essential ...

More information: Roya Anahita Mousavi et al, Association of aortic valve size with the degree of aortic valve calcification in severe high-gradient aortic stenosis, European Heart Journal ...

As your heart beats, it pumps blood from the left ventricle through the aortic valve and into the aorta, your body’s largest artery. The aortic valve is made up of three triangular flaps of ...

THE primary purpose of this report is to emphasize the relation of a high-pitched "squeaking" or "musical" systolic murmur to aortic stenosis and calcification of the aortic valve. This is not so ...

In principle, the blood volume passing through a stenotic valve (aortic stenosis) is equal to the blood volume proximal to the stenosis or in the LVOT (Figure 4). The stroke volume is equal to ...

Researchers found that at five years, patients with severe aortic stenosis who were treated with either TAVR or surgery had comparable rates of all-cause mortality or disabling stroke.

In asymptomatic patients with mild to moderate aortic stenosis, the survival is similar to age-matched controls. [1,16] The mainstay of medical treatment for these patients is simply appropriate ...