New entrants: incretin-based therapies Incretins are peptide hormones that ... With 394 candidates in development in 2006, (344 in 2005), diabetes is second only to cancer in R&D focus 3.

The incretins include the glucose-dependent insulinotropic ... Together, the GI hormones triggered by polyphenols reduce the risk of obesity and diabetes. Prof Osakabe explains, "The GI hormones ...

It mimics incretins known as GIP and GLP-1 by activating ... greater than 27 with one weight-related complication, excluding diabetes. Tirzepatide was given along with diet and exercise ...

Whether thiazolidinediones should be used to treat patients with type 2 diabetes mellitus is controversial ... and not from cardiovascular trials). Incretins, such as agonists of the glucagon ...