Immunoglobulin E: Your body makes IgE antibodies when it overreacts to substances that aren't harmful, such as pollen or pet dander. Your doctor will likely measure your IgE levels if you have a ...

The distinguishing structural feature of immunoglobulin E (IgE), the antibody responsible for allergic hypersensitivity, is the Cε2 domain pair that replaces the hinge region of IgG. The crystal ...