A novel immunoglobulin A nephropathy (IgAN) drug cut proteinuria in half, according to interim findings from the ongoing ...

Otsuka's investigational antibody sibeprenlimab approximately halved levels of this key biomarker in patients with ...

This test checks the amount of certain antibodies called immunoglobulins in your body. Antibodies are proteins that your immune cells make to fight off bacteria, viruses, and other harmful invaders.

Monoclonal means that all copies of the protein, in this case, an antibody or part of an antibody, are exactly the same. You may also hear your doctor call them monoclonal immunoglobulin ...

Sibeprenlimab targets a protein called A proliferation-inducing ligand (APRIL), and the drug is designed to limit the ...

In myeloma, the M proteins can be made up of one type of heavy chain and one type of light chain. The heavy chains are: immunoglobulin A (IgA) immunoglobulin M (IgM) immunoglobulin E (IgD ...

The Food and Drug Administration (FDA) has accepted for Priority Review the Biologics License Application (BLA) for sibeprenlimab for the treatment of immunoglobulin A nephropathy (IgAN) in adults.

Protein interactions are central to a diverse array of biological processes, but these are typically highly complex and involve the binding of multivalent ligands to several binding sites.

The FDA cleared an investigational new drug application for a phase 2 trial of GRF312 ophthalmic solution, an immunoglobulin eye drop for the treatment of dry eye disease, according to a press release ...