is also a low-affinity receptor that shows inhibitory functions like the human FcγRIIB that has an ITIM. All mouse FcγRs can attach human IgG1 and IgG3 subclasses, along with mouse IgG1, IgG2a ...

The IgG2a subclass had the highest A/I ratio (∼70) and the IgG1 subclass had the lowest ratio. Two series of soluble IgG antibodies were generated, one specific for the melanoma antigen gp75 ...