Some patients with side-effect concerns aiming to lessen their statin burden may prefer the treat-to-target approach, if they respond well to lesser-intensity statins, say researchers.

The open-label study, dubbed RACING, randomized 3780 patients with ASCVD to receive moderate-intensity rosuvastatin 10 mg plus ezetimibe 10 mg or high-intensity 20 mg rosuvastatin monotherapy.

Higher doses of statin therapy moderately increase the risk for new-onset diabetes, especially among individuals already at high risk, according to study findings published in Diabetes Endocrinology.

At six months after discharge among beneficiaries aged 66 to 75 years, 17,633 were taking high-intensity statins with high adherence, 2,605 were considered down-titrated, meaning they switched to ...

Moderate intensity statin therapy plus ezetimibe was equally effective as high-intensity statins in preventing adverse CV events in PCI patients. Menu SECTIONS. News; ...

High-intensity statin therapy upped that by 0.08 to 0.21 years QALYs (0.04 to 0.18 QALYs). The incremental cost per QALY with statin therapy compared with not taking statins ranged from £116 to £3,502 ...

Initiation of high-intensity statin therapy during the acute phase of minor, noncardiogenic stroke may increase bleeding risk, according to the results of a Chinese cohort study published in the ...

High-intensity statin users were more frequently men, at a rate of 43% versus 34% in women. Multivariable analysis confirmed male sex as a predictor of increasing use (OR 1.34; 95% CI 1.30-1.38).

As for safety, the rosuvastatin group had a higher incidence of new-onset diabetes requiring initiation of diabetes medication (7.2% vs 5.3%; HR 1.39, 95% CI 1.03-1.87) and cataract surgery (2.5% ...