Jul. 27—New insights into the underlying mechanisms of Type 2 diabetes and novel potential therapeutic targets for the disease were revealed in a recent study by a team of Texas A&M AgriLife ...

SRC-1 (steroid receptor coactivator) orchestrates glucose production in the liver, regulating the activity of a cascade of enzymes that turns sugar production on and off in the liver, said Baylor ...

The originality of our study lies in showing that the central nervous system, via sympathetic nerves, can control CREB and activate de novo glucose production by the liver if extra energy is required.

In the fasting state, the body utilizes about 2 mg glucose/ kg/min. 13 This glucose demand is perfectly matched by glucose production by the liver, 8 and glucoregulatory hormones maintain ...

One of the most confusing aspects for patients with type 2 diabetes mellitus is that they have high fasting glucose levels. This is because in these insulin-resistant patients, glucose production ...

Irvine, CA - June 25, 2021 - New research from the University of California, Irvine reveals how the circadian regulation of glucose production in the liver is lost during lung cancer progression ...

This increase in insulin suppresses hepatic glucose production, thereby preventing hyperglycemia. But in the absence of sufficient insulin, this transient increase in hepatic glucose production ...

To experimentally test this, the researchers developed a liver slice system, opposed to the standard model of using hepatocytes, or liver cells, for assessing rates of hepatic glucose production. The ...

About the Study. A randomized, double-blind, placebo-controlled trial was conducted on drug-naive individuals with prediabetes. Participants aged 35-75 years with impaired fasting glucose levels ...

Wanbao Yang, Ph.D., (left) graduate student and the study’s first author, and Shaodong Guo, Ph.D., who served as its principal investigator. (Texas A&M AgriLife photo by Tyler Morales) The study ...