The common side effect of hand-foot syndrome seen in patients taking capecitabine can be prevented by a cheap and safe topical gel containing 1% diclofenac, researchers reported in a study that ...

Hand-foot syndrome (HFS), also known as palmar-plantar erythrodysesthesia, palmar-plantar erythema, acral erythema, and Burgdorf's reaction, is a dermatologic reaction that appears on the palms of the ...

Hand-foot syndrome (also known as hand-foot reaction, palmar-plantar erythrodysesthesia, chemotherapy-associated acral erythema or Burgdorf reaction) is a cutaneous toxicity1 – 3 that is most ...

For example, hand-foot syndrome is one of the most common side effects of Xeloda. (For more about this condition, see “Hand-foot syndrome” above.) But severe skin reactions such as SJS and TEN ...

Context. Certain chemotherapy drugs, notably capecitabine, can cause a side effect known as palmar-plantar erythrodysesthesia (hand-foot syndrome), a painful swelling and inflammation of the hands ...

Correlations between development of hand–foot syndrome (HFS) and efficacy in patients receiving capecitabine (CAP)-containing therapy are reported in the literature. We explored the relationship ...

The CNIO researchers found that patients who developed hand-foot syndrome during chemotherapy with capecitabine carried these regulatory variants that resulted in the reduced expression of CDH4 ...

Breast cancer patients receiving capecitabine had a lower incidence of hand-foot syndrome after prophylactic treatment with atorvastatin and polyprenol.

This trial looked at whether vitamin B6 (pyridoxine) tablets could help relieve hand foot syndrome caused by the chemotherapy drug capecitabine. Doctors commonly use the chemotherapy drug capecitabine ...

Anywhere from 45 to 68.3 percent of people on the chemotherapy drug capecitabine develop hand-foot syndrome, according to an article published in the Cancer Investigation Journal in 2002.

To determine whether concurrent pyridoxine therapy can prevent the development of hand-foot syndrome (HFS) in patients being treated with capecitabine. Methods Chemotherapy-naive patients with GI ...