Protease inhibitors are a type of antiretroviral drug used to treat HIV. These drugs reduce the amount of virus in the body by blocking the virus from entering certain cells and making copies of ...

HIV protease forms proteins at its active site that can lead to the virus. The virus can then replicate itself throughout the body. The POM molecule provides a "second line of attack" against HIV ...

Scientists have demonstrated that HIV protease inhibitors -- crucial drugs for HIV treatment -- block a cellular enzyme important for generating the structural scaffolding for the cell nucleus.

Protease inhibitors aren’t used on their own to treat HIV; they’re used together with other treatments. They are used mainly when patients fail first-line therapies.

UCLA scientists, along with collaborators from Purdue University, have demonstrated that HIV protease inhibitors -- crucial drugs for HIV treatment -- block a cellular enzyme important for ...

The Trump administration's plan to cut funding for HIV vaccine research comes at a time when the field is making substantial ...

Ninety-six percent were male and 67 percent were over 40 years old. Thirty of the subjects were on antiretroviral regimens containing the protease inhibitor indinavir, and 37 were on regimens ...

Corticosteroid injections can lead to dysfunctions in cortisol levels in people taking HIV protease inhibitors, according to research published in the online edition of the Journal of Acquired Immune ...

Over a third of HIV-positive patients about to start antiretroviral treatment have reduced bone mineral density, French investigators report in the April 27th edition of AIDS. The researchers also ...

“The fact that HIV protease inhibitors block ZMPSTE24 and have been associated with side effects similar to those observed with a genetic deficiency in ZMPSTE24 is intriguing,” said Loren Fong ...