The new Science Express study reveals the structure of the CCR5 cell surface receptor, which most strains of HIV use to enter human immune cells. This image shows CCR5 side-by-side with alternate ...

For HIV to infect human cells, the virus binds to cell surface ... and the University of Utah describethe first high-resolution molecular structure of the hexagonal protein building block, called ...

The first describes a strategy to stabilize an important HIV structure and potentially create HIV lookalikes ... spring to undergo the dramatic changes that allow the virus to enter cells.

Once inside human cells, HIV integrates the viral genome ... a potential explanation for the evolution of the unique HIV ...

HIV then sabotages the cell machinery to make many copies of ... which have a rigid, symmetrical structure that obediently assembles into crystals, the HIV capsid is flexible and can adopt ...

In the long battle to create an effective HIV vaccine, scientists have made a major leap forward. A new study shows that a ...

As in most receptor-structure projects ... That opens up more cell types to HIV infection, and the further spread of the virus inside the body is liable to speed up the disease progression ...

The study uncovered how HIV “hides,” an understanding that could help future treatments find and eradicate it.

Lens epithelium-derived growth factor (LEDGF)/p75 is the dominant binding partner of HIV-1 integrase (IN) in human cells. We have determined the NMR structure of the integrase-binding domain (IBD ...