who is hoping to get in on the humanized glycosylation action with genetically engineered bacteria. The big advantage, he says, is that, unlike CHO cells, which tend to produce a mix of proteins ...

However, the cell also uses sugars to chemically modify proteins, altering their functions. This is called glycosylation. "Glycosylation can affect how cells attach to each other (adhesion), how ...

Japanese researchers investigated how polyamines affect the functional profile of monoclonal antibodies and their production from CHO cells, and found that spermidine supplementation contributes ...

The research team also applied this strategy to analyze HeLa cell samples under oxidative stress. They uncovered distinct spatial glycosylation patterns between the nucleus and cytoplasm ...