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Among cells producing proline-alanine, glycine-alanine, or glycine-proline ... The authors concluded that the GGGGCC RNA and proline-arginine dipeptide work together in the same toxic pathway. Finally ...
A composition, comprising: glycine; and a ... supplement for oral consumption;[17] supplying the beta-alanine, which is not part of a dipeptide, polypeptide or oligopeptide, as a single ingredient ...
C9ORF72 model mice. LOF=loss of function; GOF=gain of function; DPRs=dipeptide repeats; NR=not reported; GA=glycine-alanine; GP=glycine, proline; GR=glycine-arginine; PR=proline-arginine; ...
Many patients with amyotrophic lateral sclerosis (ALS) or frontotemporal dementia (FTD) harbor the (G4C2)n pathogenic repeat expansion in the C9orf72 gene, which leads to aggregating dipeptide ...
They figured out the chemical basis for why glycine and serine are often confused for alanine, which led them to conclude that the second check has been put in place to make sure alanine and not ...
A reaction occurs within a cluster consisting of two glycine molecules. The two amino acids become a dipeptide and a water molecule. The reaction of a dipeptide to a tripeptide within a cluster ...