L-glutamine is also used to alleviate symptoms of sickle cell disease, but how this drug works has similarly been contentious. The findings indicate that the efficacy of L-glutamine supplements likely ...

A Ludwig Cancer Research study has identified a complex chain of molecular chatter by which cancer cells, exploiting ordinary ...

The importance of glutamine metabolism for colon cancer was revealed by Masamitsu Konno Ph.D, Masaaki Miyo M.D. Ph.D, Masaki Mori, M.D. Ph.D and Hideshi Ishii M.D. Ph.D.

Macrophages are immune cells with a split personality: some fight tumors, while others help them grow. In breast cancer, most macrophages fall into the latter camp—dubbed M2-like—fueling tumor ...

Glutamine metabolism effect in tumor microenvironment cells. Credit: Oncotarget (2023). DOI: 10.18632/oncotarget.28443 A new editorial paper was published in Oncotarget, titled "Inhibition ...

On August 10, 2023, a new editorial paper was published in Oncotarget, entitled, “Inhibition of glutamine metabolism: acting on tumoral cells or on tumor microenvironment?” ...

IN 1939, it was suggested by one of us1 that the amide-nitrogen of glutamine was a source of urea-nitrogen and that urea formation was paralleled by a continuous re-synthesis of glutamine.

Researchers show that an intracellular metabolite of glutamine, alpha-ketoglutarate, plays a role in regulating cellular differentiation programs by changing the DNA-binding patterns of the ...