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Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
Pathway-focused metabolite ratio-based analysis of 49 tumor and 8 normal epithelial cell lines grown in their respective ...
Reductive carboxylation produces citrate (m+5) from glutamine (m+7) and results in the production of malate (m+3) through TCA cycle reactions ... caspase-3/7 and senescence analyses Cell viability ...
The tricarboxylic acid cycle (TCA or Krebs cycle) is classically regarded as a pathway for glucose oxidation. However, the experiments by Le and the team show that B cells oxidize glutamine when ...
The importance of glutamine has been made clear as a colon ... under the condition of glucose depletion while retaining TCA cycle activity. The cells' survival relies on a delicate balance between ...
The breakdown of glutamine is an important metabolic pathway for the health and survival of rod photoreceptors within the retina.
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