In horses, this signal is recoded into an amino acid, cysteine, allowing the KEAP1 gene to continue functioning. This mechanism demonstrates how a mutation can redirect a genetic function toward ...

In horse DNA, researchers found what looked like a catastrophic error: a premature stop codon — a three-letter genetic sequence (UGA) that tells the cell’s protein-making machinery to stop ...

The genetic switch that 'really lets horses have their cake and eat it too.’ Get the Popular Science daily newsletter💡 Breakthroughs, discoveries, and DIY tips sent every weekday. Search for: ...

How did horses become some of the greatest athletes in the animal kingdom? Researchers at Johns Hopkins Medicine may have found the answer, pinpointing a genetic mutation and evolutionary process that ...

The unique genetic change that turned horses into athletic powerhouses A new study suggests genetic changes allow horses to produce more energy, while minimizing the toll the energy takes on cells.

A genetic change that boosts a cell's aerobic capacity while also protecting it from excess stress could explain how horses became such powerful athletes, according to a new study in Science.

Researchers have revealed a secret behind horses' exceptional endurance – a mutation in the KEAP1 gene that boosts energy production while protecting against cellular oxidative stress.

This mechanism demonstrates how a mutation can redirect a genetic function toward an evolutionary advantage. This recoding is made possible by specific modifications in messenger RNA, which translates ...

"Horses can make this fire burn even hotter and make the damage even less than it would be in a species like a human," said Castiglione. The changes occurred in a key gene pathway called NRF2/KEAP1.