A genetic mutation that fuses two genes drives several different cancer types by forming networks of protein interactions that alter gene expression in cells, a study by UT Southwestern Medical Center ...

Gene drives are bits of DNA that encode various mechanisms for cheating the system and ensuring they get inherited by more than half of offspring. This means they can spread in a population even ...

Sensing damage to their DNA, cells activate internal molecular “repairmen” to stitch genes back together and adopt gene drives and their genetic cargo. Plants are different. Their cells also have a ...

This mechanism opens the door to manipulating ... but only in pollen cells containing the gene drive. The researchers used the self-pollinating plant Arabidopsis thaliana for this study in order ...

"This mechanism is an inherent remedy to the gene's selfish drive," says Yamashita, who is also a professor of biology at the Massachusetts Institute of Technology and an investigator of the ...

A research team at KAIST has identified the core gene expression networks regulated by key proteins that fundamentally drive phenomena ... had uncovered essential mechanisms controlling gene ...

Men who carry two copies of a common genetic variant are twice as likely to develop dementia than women with the same ...

A study published in Nature Genetics reveals new insights into how medulloblastoma, the most common malignant brain tumor of childhood, can arise as the cerebellum develops. Researchers discovered ...

Researchers discovered that the same gene, ZIC1, can drive highly similar cancers by distinct, context-dependent mechanisms. Led by researchers at Baylor College of Medicine, Texas Children’s Cancer ...