A study published today in Current Biology finds that children and adults have different concentrations of a key brain messenger called gamma-aminobutyric acid or GABA. This messenger stabilizes ...

A distinction is often made between classical small-molecule neurotransmitters, including glutamate, GABA, glycine ... but it does not specify mechanism and, therefore, also extends to gaseous ...

High GABA production decreases nerve activity, and it is through this mechanism the researchers hypothesize the liver influences blood glucose levels. "When the liver produces GABA, it decreases ...

CryoEM structures show GABA-A receptors with GABA and modulators. Inhibitors constrict the ion channel via allosteric mechanisms. Benzodiazepines help GABA twist it, opening it. Researchers led by ...

Justin Lee said, "From this study, we reveal the novel mechanism of how Alzheimer's patients might lose their memory. We also propose new therapeutic targets, which include GABA production and ...

“We combine a comprehensive view of clinical development strategy, regulatory considerations and intellectual property to find differentiated assets with validated mechanisms of action. GABA-A ...

Zebrafish possess mechanism to self-repair their retinas with restoration of vision. Low levels of GABA, an inhibitory neurotransmitter found to trigger self-repair of damaged retina in zebrafish.

And, hence, clarithromycin is a GABA-A antagonist and it's counteracting that GABA mechanism. There are the other medications being studied. Ones like serdexmethylphenidate, which is a ...