In muscle and fat cells, insulin stimulates the delivery of the glucose transporter GLUT4 from an intracellular location to the cell surface, where it facilitates the reduction of plasma glucose ...

The glucose transporter GLUT4 ensures controlled glucose uptake into fat and muscle cells. By targeting several steps in the membrane trafficking of GLUT4, insulin signalling allows tight ...

In addition to medical interventions, certain foods may help support neurogenesis by increasing Brain-Derived Neurotrophic ...

GLUT4 messenger RNA and protein are reduced in adipocytes in many insulin-resistant states, 6 often long before type 2 diabetes develops. 20 We previously reported that genetic knockout of GLUT4 ...

They show here that GLUT4 is inserted into the myotube plasma membrane at regions of membrane ruffling, where cytoskeletal remodeling takes place. Perturbing the cytoskeleton with specific drugs ...

Using high-resolution microscopy, researchers have shown how insulin prompts fat cells to take in glucose in a rat model. By studying the surface of healthy, live fat cells in rats, researchers ...

Effect of creatine supplementation on muscle GLUT4 protein content during immobilization and subsequent rehabilitation training.

Adipose tissue glucose transport and GLUT4 levels regulate systemic insulin sensitivity and whole-body energy balance, which have implications for the pathogenesis and treatment of obesity and diab ...

Commenting on their collective results the team noted, “Thus, expression of the glucose transporter GLUT4 increases during aging in NSCs in vivo, and knockout of this transporter boosts NSC ...

Researchers at Daiichi Sankyo Co. Ltd. have developed a xanthene compound that can promote glucose uptake by GLUT4 into skeletal muscle.

Cite this: Effect of Oral Creatine Supplementation on Human Muscle GLUT4 Protein Content After Immobilization - Medscape - Jan 01, 2001.