Surprisingly, GLP-1 receptor signaling promotes glucose-stimulated insulin secretion independent of the mode of glucose entry. Based on rates of D -xylose absorption, GLP-1 receptor blockade did ...

Glucagon-like peptide 1 (GLP-1) is released from neuroendocrine cells in the intestine in the postprandial state and augments glucose-stimulated insulin secretion from pancreatic β cells. To ...

However, significant differences in beta-cell susceptibility to glucagon-like peptide-1 (GLP-1) appear to exist independent of insulin sensitivity, according to the researchers. News News CME CME ...

GLP-1 is a hormone that regulates blood sugar, appetite and digestion. A diet rich in high-fiber foods may help your body ...

GLP-1 is a hormone that regulates glucose levels in the body by stimulating the secretion of insulin, and GLP-1 also inhibits appetite. "We have found that GLP-1 is reduced by up to 25% among ...

GLP-1 promotes adipogenesis through its effects on insulin sensitivity, stimulation of fatty acid synthesis in adipose tissue 9 and attenuation of the lipolytic action of glucagons. 10,11 Obese ...

Despite the impaired incretin effect seen in patients with type 2 diabetes, the ability of GLP-1, when present, to elicit the secretion of insulin by pancreatic beta cells appears to be preserved ...

PGLP-1, a novel long-acting dual-function GLP-1 analog, ameliorates streptozotocin-induced hyperglycemia and inhibits body weight loss. The FASEB Journal , 2017; fj.201700002R DOI: 10.1096/fj ...

Dennis P. Scanlon, PhD: Let’s turn for a moment and talk about the new insulin GLP-1 (glucagon-like peptide-1) combinations—the combination therapies. Mary Ann, maybe I’ll start with you ...

Individualized ocular characteristics should be considered before starting GLP-1 RA therapies for weight loss and diabetes management.

Moreover, the impact of GLP-1r blockade was also comparable in the groups, indicating that endogenous GLP-1 contributes significantly to postprandial insulin secretion in diabetic subjects.