Gene therapy involves the introduction of functional genes into cells to replace or correct defective genes. Nucleic acids, such as viral vectors or synthetic nucleic acid molecules, are used to ...

A team of researchers at Karolinska Institutet has developed a novel tool for genetic research. The study, published in ...

Nucleic acid therapeutics use engineered sequences ... In that therapy, ASOs force motor neurons to produce a functional version of a protein that is absent in SMA patients. The development ...

Guzikowski et al, Functional specificity of liquid-liquid ... that are enriched in specific protein-protein or ...

ELRIG, a not-for-profit, volunteer-led organization for the drug discovery community, today announced the keynote speakers for Therapeutic Oligonucleotides 2025 taking place at the AstraZeneca R&D ...

Nucleic acid unwinding is an essential step in many ... Among the pending mechanistic issues is the functional relevance of the six-fold versus three-fold architectures that have been observed ...

Adenosine deaminase 2 (ADA2) has been identified as a regulator of toll-like receptor 9 (TLR9) activation in response to ...

View Full Profile. Learn about our Editorial Policies. To obtain high-quality, purified nucleic acids, scientists can use several different methods, including phenol-chloroform extraction, cesium ...

The Functional Genomics and Microbiome Core (FGM ... This core uses tools and services, such as highly parallel nucleic acid sequencing, mass spectrometry-guided metabolomics and proteomics, and super ...