An international team led by Einstein Professor Cecilia Clementi in the Department of Physics at Freie Universität Berlin has ...

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in ...

New study suggests more than 200 types of misfolded proteins could be associated with age-related cognitive decline ...

Aging-related diseases, including cancer, cardiovascular disorders and type 2 diabetes, are associated with defects in ...

Researchers at the University of Michigan found that mitochondria also accumulate misfolded proteins, which kills β-cells.

An international team led by Einstein Professor Cecilia Clementi in the Department of Physics at Freie Universität Berlin ...

The wiggly targets known to scientists as “intrinsically disordered proteins” have for decades eluded capture by custom-made ...

Scaletti C, et al. Hydrogen bonding heterogeneity correlates with protein folding transition state passage time as revealed by data sonification. Proc Natl Acad Sci U S A. 2024;121(22):e2319094121.

A surprising new study has uncovered over 200 misfolded proteins in the brains of aging rats with cognitive decline, beyond ...

Researchers have developed a method to evaluate the folding stability of a million proteins simultaneously. DNA libraries were used to generate protein -- DNA complexes that were treated with ...

Scientists have been studying how proteins fold for decades. This research got a boost in late 2020, when AlphaFold proved it could predict protein structures with great accuracy.

(4) Unlike folded proteins, intrinsically disordered proteins lack a stable, three-dimensional structure. Instead, they exhibit conformational heterogeneity and interconvert between different states. ...