These drugs are known to act by targeting specific steps in the folate biosynthetic pathway, and their combined activity is far greater than the sum of their individual activities. For the last ...

This result was achieved through metabolic engineering, the modulation of the biosynthesis pathway of a plant compound. Their new study shows that about half of the folate content in these rice ...

xylanisolvens (BXΔfolP) by knocking out the folp gene in the folate biosynthetic pathway. Gavages with BXΔfolP failed to alleviate NAFLD in mice. This study demonstrates the anti-NAFLD effect of ...