Finally, we have defined biomarkers that predict sensitivity and resistance to ferroptosis, opening the possibility of precision medicines that induce ferroptosis for treating a variety of cancers.

By establishing an iron overload-induced hepatic ferroptosis model, scientists from Japan have identified iFerroptosis—an ...

However, the origin of this lipid peroxidation that causes ferroptosis has remained a topic of debate," explains Professor Ken-ichi Yamada of Kyushu University's Faculty of Pharmaceutical Sciences ...

"Interestingly, in cancer cells that are less susceptible to ferroptosis, lipid peroxidation occurred in the lysosomes, but this did not lead to lysosomal membrane damage," continues Yamada.

Zooming in and out of ferroptosis in human disease. Higher Education Press . Journal Frontiers of Medicine DOI 10.1007/s11684-023-0992-z ...

Ferroptosis, characterized by iron-mediated lipid peroxidation, holds the potential to counter resistance by selectively targeting cancer cells’ defense mechanisms, paving the way for new ...

Ferroptosis is a form of programmed cell death, distinct from apoptosis, that was identified in 2012. The process is driven by the iron-dependent oxidative degeneration of lipids. Image Credit ...

Ferroptosis, an iron-mediated lipid peroxidation can be used to overcome cancer treatment resistance. Digestive tract cancer is one of the life-threatening tumor conditions among all cancers.

News tagged with lipid peroxidation. Date. 6 hours 12 hours 1 day 3 days all. Rank. Last day 1 week 1 month all. ... Study reveals previously unrecognized role of CEPT1 in suppressing ferroptosis ...