Iron-dependent ferroptosis, a non-apoptotic cell death mechanism, is gaining attention for its role in immune suppression.

Moreover, h15-LOX-2 and other LOX enzymes may be involved in ferroptosis, a form of iron-dependent cell death associated with lipid peroxidation. In this case, inhibition of the enzyme may be ...

A notable aspect of the interplay between HDL-C functionality and iron homeostasis is the process of ferroptosis, induced by lipid peroxidation and disturbed iron balance, characterized by the ...

Neurizon Therapeutics Limited (“Neurizon”), a clinical-stage biotech company dedicated to advancing treatments for ...

(2020) Ferroptosis occurs through an osmotic mechanism and propagates independently of cell rupture. Nat Cell Biol. Sep 22; (9):1042-1048. Katikaneni A, Jelcic M, Gerlach GF, Ma Y, Overholtzer M, ...

Moreover, h15-LOX-2 and other LOX enzymes may be involved in ferroptosis, a form of iron-dependent cell death associated with lipid peroxidation. In this case, inhibition of the enzyme may be ...