The isolation of cytolytic immunoglobulin G (IgG) antibodies against the cell-surface protein human Fas in the late-1980s was another of the pioneering discoveries in the field of apoptosis ...

As the Fas receptor–ligand pathway is involved in c-myc-induced apoptosis in fibroblasts 6 and MYCN overexpression sensitizes NB cells to apoptotic signals 2, one or more components of this ...