Fas-mediated apoptosis is essential for the elimination of cells, and impaired apoptosis can have severe detrimental consequences. Bisindolylmaleimide VIII potentiated Fas-mediated apoptosis in ...

Multiple myeloma (MM) is an incurable malignancy of terminally differentiated B-lymphoid cells. Here, we investigate the role of Fas apoptosis inhibitory molecule (FAIM) in MM. We demonstrate that ...

Apoptosis was quantified by fluorescein isothiocyanate-conjugated annexin V/flow cytometric analysis and by DNA fragmentation. Fas expression was measured by flow cytometric analysis.

Introduction Substance P (SP) and its preferred receptor, the neurokinin-1 receptor (NK-1 R), are expressed in human tenocytes and this is particularly seen in the tenocytes in cases of tendinosis.

A new study has discovered a promising approach to improve the efficacy of adoptive cell therapies for cancer. The research, published in Molecular Therapy: Nucleic Acids, describes the development of ...

Singapore scientists have made a novel discovery about how gene, "Fas-apoptosis inhibitory molecule," protects both immune and liver cells from programmed cell death. Their research is published ...

In support of this, cells carrying mutations in FasL, or its receptor Fas, were much less likely to undergo apoptosis when challenged with Aβ25-35. In addition, the researchers were able to show that ...

The influence of doxorubicin on apoptosis was studied by flow cytometry analysis. ... Doxorubicin Induces Fas-Mediated Apoptosis in Human Thyroid Carcinoma Cells - Medscape - Apr 01, 2004.