It has long been thought that two enzymes, the kinases CDC7 and CDK2, are both needed to trigger DNA replication in mammalian cells. This view is challenged by evidence that offers a revised view ...

Enzyme Critical In DNA Replication Identified Date: July 6, 2007 Source: NIH/National Institute of Environmental Health Sciences Summary: In the journal Science, researchers report an important ...

An enzyme essential for DNA replication and repair in humans works in a way that might be exploited as anti-cancer therapy, say researchers. Share: Facebook Twitter Pinterest LinkedIN Email.

MichaelTaylor3d. Functions of DNA polymerase enzymes. Since Arthur Kornberg was awarded the Nobel Prize in 1959 for determining the roles of DNA polymerases during DNA replication, it has been ...

Cancer-Causing Enzyme Acts during DNA Replication February 2, 2016 Scientists at Indiana University (IU) have identified a genetic mechanism that is likely to drive mutations that can lead to cancer.

Key role found for enzymes in DNA replication and sensitivity to chemotherapeutic drugs. Institute for Research in Biomedicine (IRB Barcelona) Journal Science Advances DOI 10.1126/sciadv.aat4985.

The proteins that drive DNA replication—the force behind cellular growth and reproduction—are some of the most complex machines on Earth. The multistep replication process involves hundreds of ...

A 'gap in the armor' of DNA may allow enzyme to trigger cancer-causing mutations. ... Research on the effect of the enzyme APOBEC3G on DNA replication was conducted in the bacteria Escherichia coli.

A protein that is involved in determining which enzymes cut or unwind DNA during the replication process has been identified in a new study. In a new paper published in Nature Communications, an ...

It is often found in some viruses and plays a key role in certain biological processes, such as cell replication or repair. Single-stranded DNA is also used in many technologies (sequencing, gene ...

Organisms today employ multiple enzymes, proteins and RNA, to catalyze biochemical reactions that are essential for life. According to the RNA world model, DNA and proteins were absent when life ...