Angiotensin converting enzyme inhibitors and angiotensin receptor blockers are commonly used to treat hypertension and/or a range of progressive end-organ diseases. The success of each of these ...

ACE inhibition is a sufficiently well accepted treatment modality, and most of the guidelines addressing treatment of hypertension, renal disease, and/or cardiovascular disease have this ...

Small-molecule enzyme-inhibitors often display insufficient affinity and selectivity for their targets causing unwanted side effects when used as drugs. Molecularly imprinted polymers prepared ...

Life as we know it wouldn’t exist without enzymes. These tiny proteins, found in every living organism, are the catalysts ...

Other NSAIDs do not have this effect. Cox-2 inhibitors are a newer form of prescription NSAID. As you might guess, they only affect Cox-2 enzymes and not Cox-1. Two of them -- Bextra and Vioxx ...

In the brain, the enzyme ABHD6 degrades a key endocannabinoid molecule known as 2-arachidonoylglycerol (2-AG). With the discovery in 2016 that whole-body inhibition of ABHD6 reduced body weight ...

Influencing their activity can control their rates of reaction. Different chemicals can influence enzyme activity. Inhibitors can be used to stop an enzyme from binding to its substrate.

Fatty acid synthase, the enzyme responsible for fatty acid production in cells, may be a therapeutic target for IPF, a mouse ...