Lineage tracing in transgenic mice allows the study of stem, progenitor and cancer cells in their native environment and can give quantitative insight into cell behaviour. Experiments have two ...

Angiogenesis research investigates the formation of new blood vessels in wound healing, tumour growth and embryonic development. Circulating, bone marrow-derived endothelial progenitor cells (EPCs ...

Breast cancer often relapses in distant organs even when complete regression of primary tumors is achieved after initial ...

Characterizing progenitor cells in developing and injured spinal cord: Insights from single-nucleus transcriptomics and lineage tracing Article Publication Date 6-Jan-2025 ...

By intersectional lineage tracing technology, researchers pinpointed that endocardium-derived liver vasculature is derived from sinus venosus endocardium, which is also the origin of coronary vessels.

Lineage Announces Notice of Allowance of Two Patents Covering Processes for Manufacturing Allogeneic Oligodendrocyte Progenitor and Retinal Pigmented Epithelium Cells October 10, 2022 08:00 AM ...

Through single-cell and lineage tracing analyses, the researchers revealed that some astrocytes could transdifferentiate into oligodendrocytes under injury-induced conditions, thereby contributing ...

Lineage Cell Therapeutics, Inc., ... New Drug amendment to the U.S. Food and Drug Administration, for OPC1, its investigational allogeneic oligodendrocyte progenitor cell transplant, for ...

The new research published in PNAS used single-cell RNA sequencing analysis, protein expression studies, and a new lineage-tracing tool to reveal details of early lung formation in a fetal mouse ...

image: Genetic lineage tracing shows that endocardial cells in the heart (red) contribute to vasculature in the liver of a day-10.5 embryo (E10.5). view more Credit: Image from Dr. ZHOU Bin's lab ...