New genetic tools reveal the dual roles of senescent cells in liver disease—macrophages drive fibrosis, while endothelial ...

Lineage tracing in transgenic mice allows the study of stem, progenitor and cancer cells in their native environment and can give quantitative insight into cell behaviour. Experiments have two ...

By intersectional lineage tracing technology, researchers pinpointed that endocardium-derived liver vasculature is derived from sinus venosus endocardium, which is also the origin of coronary vessels.

Through single-cell and lineage tracing analyses, the researchers revealed that some astrocytes could transdifferentiate into oligodendrocytes under injury-induced conditions, thereby contributing ...

Cilostazol Enhances Mobilization of Circulating Endothelial Progenitor Cells and Improves Endothelium-Dependent Function in Patients at High Risk of Cardiovascular Disease, Angiology, 67, 7, (638 ...

Characterizing progenitor cells in developing and injured spinal cord: Insights from single-nucleus transcriptomics and lineage tracing Article Publication Date 6-Jan-2025 ...

Lineage Announces Notice of Allowance of Two Patents Covering Processes for Manufacturing Allogeneic Oligodendrocyte Progenitor and Retinal Pigmented Epithelium Cells October 10, 2022 08:00 AM ...

The new research published in PNAS used single-cell RNA sequencing analysis, protein expression studies, and a new lineage-tracing tool to reveal details of early lung formation in a fetal mouse ...

image: Genetic lineage tracing shows that endocardial cells in the heart (red) contribute to vasculature in the liver of a day-10.5 embryo (E10.5). view more Credit: Image from Dr. ZHOU Bin's lab ...