Endothelial cells contribute to a subset of cardiac fibroblasts by undergoing endothelial-to-mesenchymal transition, but whether cardiac fibroblasts can adopt an endothelial cell fate and directly ...

More information: Xiaolong Zhu et al, Acetate controls endothelial-to-mesenchymal transition, Cell Metabolism (2023). DOI: 10.1016/j.cmet.2023.05.010 Journal information: Cell Metabolism ...

Endothelial-mesenchymal transition (EndoMT, also termed as EndMT), a biological process resulting in the formation of mesenchymal (or lineage-committed) phenotypes from endothelial cells (lining ...

Oncotarget published "Carcinoma cells that have undergone an epithelial-mesenchymal transition differentiate into endothelial cells and contribute to tumor growth" which reported that the authors ...

Atherosclerosis, a disease characterized by the accumulation of lipids and inflammatory cells in the arterial wall, is a significant cause of cardiovascular events. A key process in atherosclerosis is ...

One such molecule is TGF-β, which is known to induce endothelial-mesenchymal transition (EndMT), a process that involves the conversion of endothelial cells, which comprise the inner lining of ...

Tumors are made up of millions of cells, and removing all of these cells surgically or eliminating them with medication becomes much more difficult after the cancer has spread to other parts of the ...

Kidney fibrosis, a common endpoint of chronic kidney disease (CKD), is strongly linked to aging, with cellular senescence ...

Tumors are made up of millions of cells, and removing all of these cells surgically or eliminating them with medication becomes much ...

The phenomenon of epithelial–mesenchymal transition (EMT) has gained attention in the field of cancer biology for its potential contribution to the progression of carcinomas. Tumor EMT is a ...

Researchers develop a novel reporting system called the “EndoMT reporter endothelial cells” or EMRECs, to visualize the intermediate phases of EndoMT. Using RNA-sequencing and gene expression ...