Cardiac abnormalities can occur in patients treated with doxorubicin for lymphoma in the absence of CHF, even in patients who received moderate anthracycline doses. Male sex, older age, higher dose of ...

Daunorubicin appeared associated with a lower cardiomyopathy risk than doxorubicin among childhood cancer survivors, according to a multicenter cohort study published in JAMA Oncology.Results also ...

TITLE: Cardiotoxicity of doxorubicin is mediated through mitochondrial iron accumulation AUTHOR CONTACT: Hossein Ardehali Northwestern University, Chicago, IL, USA Phone: 312-503-2342; Fax: 312 ...

The drug daunorubicin was associated with decreased cardiomyopathy risk when compared to doxorubicin, the study showed. Mitoxantrone, another chemotherapy, appeared to have greater long-term ...

Doxorubicin (DOX) is a red-colored anticancer drug that carries serious side effects for the heart, including cardiac muscle deterioration (cardiomyopathy) and scar tissue accumulation in the ...

Doxorubicin cardiomyopathy is associated with a decrease in calcium release channel of the sarcoplasmic reticulum in a chronic rabbit model. J. Clin. Invest. 91, 1697–1705 (1993).

Doxorubicin HCl 2mg/mL; soln for IV inj. Risk of cardiomyopathy (including left ventricular failure), arrhythmias. Pre-existing heart disease or risk thereof. Obtain CBCs, bilirubin, SGOT/SGPT ...

In long-term survivors of childhood cancer, cardiovascular disease is a leading cause of early death from non-cancer causes. In a new study, published Jan. 31 in JAMA Oncology, researchers ...

Researchers retrospectively evaluated five studies in which children and adolescents with cancer received between 100 mg/m² and 600 mg/m² doxorubicin and were randomly assigned to dexrazoxane ...

Doxorubicin HCl 10mg/vial, 20mg/vial, 50mg/vial; pwd for IV inj after reconstitution; contains lactose. Risk of cardiomyopathy (including left ventricular failure), arrhythmias. Pre-existing heart ...