These gene variants are known to occur in congenital sucrase-isomaltase deficiency, a rare genetic form of disaccharide malabsorption that shares many features of IBS, including diarrhea ...

Other examples include the isolated or combined disaccharide malabsorption syndrome, which prevents the absorption of sucrose, lactose and other disaccharides, either one in particular or all ...

Congenital Sucrase-Isomaltase Deficiency (CSID) is an autosomal recessive disorder characterised by mutations in the gene that encodes the sucrase-isomaltase enzyme complex.

Dear Dr. Roach: What can you tell me about fructose intolerance and/or malabsorption? Is there a genetic predisposition to this? Can it develop later in life? What are the symptoms, and how is it ...

FODMAPs are “fermentable oligosaccharides, disaccharides, monosaccharides and polyols.” These are hard for many people to digest, and they include fructose, lactose, gluten and some sweeteners.