Flaviviridae viruses, illustration. The Flaviviridae comprise a family of RNA viruses known for causing serious vector-borne diseases such as dengue fever, zika, and yellow fever.

Viruses of the family Flaviviridae, including Japanese encephalitis virus (JEV), dengue virus (DENV), Zika virus (ZIKV), West Nile virus (WNV), and tick-borne encephalitis virus, are significant ...

The researchers focused on two stages of viral replication: at the beginning of RNA synthesis and during RNA elongation. Their structural analyses revealed not only the intricate mechanics behind how ...

Dengue virus is the most common mosquito-spread virus globally, but generally relatively rare in the continental United States. However, the US Centers for Disease Control and Prevention warned ...

During infection, flavivirus core proteins migrate to the nucleus of host cells to aid viral replication. Researchers have identified a transporter protein, called importin-7 (IPO7), as crucial for ...

Infections with dengue virus have increased significantly over the past two decades and it is estimated that >3 billion people live in at-risk areas worldwide. Whitehead and colleagues discuss ...