Skin immunity is mediated mainly by Langerhans cells and Vγ3 T cell receptor (TCR)-expressing dendritic epidermal T cells (DETCs), which are in intimate contact with neighboring cells.

The study of transcriptomic signatures, and of migratory and T cell-stimulatory properties, has unravelled the functional specialization that exists among skin antigen-presenting cell (APC) types.

By knocking out or beguiling dendritic cells, they slip the defenses of the immune system and sack the unsuspecting body. New research shows that one of the most common types of skin cancer has ...

During a live event, Gary J. Schiller, MD, reviewed the diagnostics and characteristics of blastic plasmacytoid dendritic ...

But he also says he finds it fascinating to figure out the ways dendritic cells and nociceptors work together as a neuroimmune unit in both skin and mucosal surfaces. “They just use different means to ...

The first-in-class antibody-drug conjugate (ADC) pivekimab sunirine (PVEK) demonstrated promising efficacy and high response ...

Design_Cells / Shutterstock Dendritic cells are found in tissue that has contact with the outside environment, such as lung mucosa, epithelial cells of the skin, and the linings of the nose and ...

A microscope image of immune cells (Langerhans cells in red, dendritic epidermal T cells in green) spreading out among the epithelial cells in the skin Greco Lab View 1 Image ...

In patients with an advanced type of skin cancer called cutaneous squamous cell carcinoma (cSCC), those who received the ...

Skin-Resident Murine Dendritic Cell Subsets Promote Distinct and Opposing Antigen-Specific T Helper Cell Responses. Immunity , 2011; DOI: 10.1016/j.immuni.2011.06.005 Cite This Page : ...

BPDCN is an aggressive type of blood cancer that originates from plasmacytoid dendritic cells (pDCs), a component ... but around 80% of cases involve the skin, according to the Leukemia and ...

By knocking out or beguiling dendritic cells, they slip the defenses of the immune system and sack the unsuspecting body. New research shows that one of the most common types of skin cancer has ...