In the 1990s, the lab of Frances Arnold showed how we can turn evolution to our advantage by manipulating microbes into evolving in a certain way. Now Arnold's team is using the technique to ...

The enzyme developed in Arnold’s lab can create beta-lactam, gamma-lactam, and delta-lactam molecules. Credit: Caltech “In traditional synthetic chemistry, we have to tack extra reactive groups onto ...

May 10 (UPI) --Scientists have developed a better way to build new antibiotics. Using a method known as directed evolution, researchers successfully synthesized beta-lactams, a molecular structure ...

Successful synthesis of gamma-lactam rings from hydrocarbons Date: March 1, 2018 Source: Institute for Basic Science Summary: Scientists have designed a novel strategy to synthesize ring-shaped ...

Researchers have made a significant breakthrough in the field of asymmetric synthesis of beta-lactams, which are prominent in bioactive compounds. Their innovative approach employs nickel and ...

De-escalation of beta-lactam antibiotics was associated with a decreased risk of new resistance development compared with no change in beta-lactam antibiotic use, researchers found.

Patients who experienced allergic reactions after the beta-lactam challenge had them within 72 hours of admission, with four (2.2%) having reactions in an inpatient setting and one (0.5%) in the ED.