Oral solid dosage forms such as tablets and capsules remain the most widely used method for delivering drug products to ...

Scientists at EPFL and AstraZeneca have developed a method to map the atomic-level structure of amorphous drugs, demonstrated on a GLP-1 receptor agonist candidate for diabetes and obesity treatment.

The advanced DSC technologies allow accurate characterization of a wide range of amorphous and crystalline ... of polymorphic forms of a substance Study of solid-state kinetics such as accelerated ...

The crystallinity of the drug was decreased, which indicated a more amorphous nature of the drug in XRD and DSC studies. Compared to pure drug dispersion, the optimized formulation exhibited a 3. ...

As this instability has a potentially negative impact on storage and drug potency ... near infrared and modulated DSC. However, there are few techniques that can quantify amorphous contents below 1%.

In this work, TASC was used in direct comparison to DSC to investigate changes ... Wiliams, R. O. (2015) Amorphous solid dispersions and nanocrystal technologies for poorly water-soluble drug delivery ...

Amorphous materials, which include substances like glass, consist of disordered particles that lack repeating patterns. A crucial aspect of using machine-learning models to predict the physical ...