DNA Repair (Amst) 1, 983–994 (2002). Durocher, D. & Jackson, S. P. DNA-PK, ATM and ATR as sensors of DNA damage: variations on a theme? Curr Opin Cell Biol 13, 225–231 (2001). Hartwell ...
On removal of the inhibitor, the number of B cells with chromosome aberrations decreased, concomitant with the increase in ATM activity. This indicates that, in addition to its role in DNA repair ...
New findings show that the mitochondria powering our cells also control the ability of a DNA repair protein to suppress the senescence-associated secretory phenotype (SASP), which causes zombie-like ...
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BRCA1 gene mutations may not be key to prostate cancer initiation, as previously thoughtand genetic variants in DNA damage repair and response genes are known to have a role in disease progression. For example, men with inherited or acquired mutations in BRCA2 or ATM genes are at ...
Labroots’ virtual events are designed to spark impactful scientific discussions while connecting with individuals worldwide ...
Homologous recombination plays essential roles in the repair of DNA double strand breaks (DSBs ... studies of inherited cancer predisposition syndromes. These include the ATM and NBS1 proteins that ...
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Breakthrough study sheds light on Pol-theta’s role in DNA repair and cancerDNA repair proteins act like the body's editors, constantly finding and reversing damage to our genetic code. Researchers have long struggled to understand how cancer cells hijack one of these ...
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