Here's how it worked: Data, 0 or 1, was represented by a short piece of single-stranded DNA, called an oligonucleotide, that contained a series of bases: adenine, thymine, guanine and cytosine.

Standard schematic of oligonucleotide activities in pathogenesis disease progression. Decoys bind to transcription factors of targeted DNA at the earliest phase. Subsequently, antisense RNA, small ...

These programmable arrays, assembled from single-stranded DNA oligonucleotides, allow for highly scalable and adaptable circuits. Each DPGA supports over 100 billion unique configurations ...

Notable oligonucleotide synthesis companies such ... Future synthesis, Integrated DNA Technologies, Kaneka Eurogentec, LGC Biosearch Technologies, Microsynth, Nitto Avecia, Ribo Biotechnology ...

Single-cell transcriptomics has revolutionized the study of cellular diversity and function by enabling gene expression ...

LCGC International spoke with Daniel Meston and Dwight Stoll from Gustavus Adolphus College in St. Peter, Minnesota, USA, ...

Rolling-circle amplification (RCA) driven by DNA polymerase can replicate circularized oligonucleotide probes with either linear or geometric kinetics under isothermal conditions. In the presence ...

Oligonucleotide therapeutics are becoming increasingly popular, with scientists developing treatments for rare diseases, cancer, and respiratory disorders. To ensure their quality, researchers must ...

It is also used at several stages during the synthesis of double-stranded cDNA, during addition of linkers to blunt-ended DNA, to remove oligonucleotide primers from PCR and, in general ...