The high specificity and stability of the guanine-cytosine base pair are essential for maintaining the integrity of the genetic information. Guanine-rich sequences in DNA can form unique secondary ...

The thymine-adenine (T-A) base pair is held together by fewer hydrogen bonds compared to the guanine-cytosine (G-C) base pair, which has three hydrogen bonds. The complementary base pairing in DNA ...

It is a qualitative, quantitative, and efficient approach to identify methylated cytosine at single base-pair resolution. 3 Cytosine methylation occurs when a methyl group binds to the fifth carbon of ...