If the disulfide can be re-bridged following conjugation, there will be fewer possible drug positional isomers than with the single thiol approach, with the DAR distribution limited to between 0 ...

Mersana Therapeutics, Inc. announced that new data related to its conjugation technology used to create next-generation ADCs is being presented in a poster session at the 2013 Annual Meeting of the ...

Attaching the conjugate. In a Cold Spring Harbor Protocol 1, Berg and Fishman explain that most antibody-labeling strategies use one of four modes of attaching a small molecule to an antibody.For ...

AMSTERDAM--(BUSINESS WIRE)--Synaffix BV, a biotechnology company exclusively focused on the development of industry-leading antibody-drug conjugate (ADC) technology, today announced a new set of ...

Scientists develop method to quickly enhance immune-system proteins. Rice University. Journal Bioconjugate Chemistry Funder Robert Welch Foundation, Cancer Prevention and Research Institute of Texas ...

CAMBRIDGE, England& BOSTON---- Bicycle Therapeutics plc, a biotechnology company pioneering a new and differentiated class of therapeutics based on its proprietary bicyclic peptide technology ...

At low doses, Mersana's new Fleximer antibody-drug conjugation technology completely cured HER2-positive breast tumors in mice. In the new research findings, the key is how the polymer is attached ...

Bacteria present in the mouth may delay the flavour response for some fruit, vegetables, and wine, according to a new study from Firmenich. Scientists from the Swiss company’s Corporate R&D Division ...