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Patients are prone to airway contraction when cells lose cyclic adenosine monophosphate. Patients with asthma had higher average serum cAMP levels than patients who did not have asthma.
Binding to these receptors inhibits adenyl cyclase activity which lowers cyclic adenosine monophosphate (cAMP). Thus the firing of new impulses at the sinus node is prevented and there is slowing ...
Tregs can transfer cyclic adenosine monophosphate (cAMP) to effector T cells, suggesting an association between Tregs' immune-evasion role and the intracellular cAMP pathway. In this study ...
Adenosine is a nucleoside that occurs naturally in all cells of the body. Chemically it is 6-amino-9-beta-D-ribofuranosyl-9-H-purine. Adenosine is made up of adenine attached to a ribose sugar ...
THE biologic role of cyclic AMP (adenosine 3′,5′-monophosphate), at least as it is understood today, is shown in Figure 1. After release from an endocrine gland, a hormone is transported to ...
Using genetic and biochemical assays, we found that Acb2 bound the OptS-synthesized nucleotide, 2′,3′-cyclic adenosine monophosphate (2′,3′-c-di-AMP); however, 2′,3′-c-di-AMP was synthesized ...
to cyclic-3, 5-adenosine monophosphate (cyclic AMP). Increased cyclic AMP levels cause relaxation of bronchial smooth muscle. Prime before using for the first time, when the inhaler has not been ...
Dipyridamole inhibits the uptake of adenosine into platelets ... platelet adenylate cyclase and increasing platelet cyclic-3',5'-adenosine monophosphate (cAMP) levels. Via this mechanism, platelet ...
Yu and colleagues recently reported evidence that underscores the importance of the cytoplasmic DNA sensor cyclic guanosine monophosphate–adenosine monophosphate (cGAMP) synthase (cGAS ...