Craniosynostosis is the early fusion of the cranial sutures, which poses numerous diagnostic and medical complications. It is a frequent abnormality that affects 3–5 out of every 10,000 babies.

"By examining the very earliest stages of coronal suture development at cellular resolution, our study provides key insights into why this suture is particularly vulnerable to defects in newborns with ...

In contrast, mice with craniosynostosis had far fewer suture stem cells, ... The developing mouse coronal suture at single-cell resolution. Nature Communications, 2021; 12 (1) ...

Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nature Communications , 2021; 12 (1) DOI: 10.1038/s41467-021-27402-5 Cite This Page : ...

A new study in Nature Communications presents a detailed cellular atlas of the developing coronal suture, ... the brain grows but are absent in children with a birth defect called craniosynostosis.

Holmes, G. et al., Single-cell analysis identifies a key role for Hhip in murine coronal suture development. Nature Communications, December 8, 2021, DOI: 10.1038/s41467-021-27402-5 About the ...

We found that disruption of fibronectin expression would cause patent fontanelle and premature fused suture, known as craniosynostosis. ... Alizarin red staining of mineralized frontal and parietal ...