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Each eukaryotic chromosome is composed of DNA coiled and condensed around nuclear proteins called histones. Humans inherit one set of chromosomes from their mother and a second set from their father.
The model proposes a general mechanism for the formation of condensed mitotic chromosomes, which is applicable to all eukaryotes across a broad range of genome sizes. "We expect that following our ...
Eukaryotic cells, including human cells, form paired condensed chromosomes before cell division. The paired chromosomes are then equally divided into the daughter cells. Prokaryotic cells ...
In preparation, it tidies up by packing the DNA into dense, sausagelike rods, the chromosomes’ most familiar form. Scientists have watched that process through a microscope for decades: The DNA ...
During cell division, chromosomes begin to condense and remain so until the division is complete. A number of proteins in the cell control the condensation, but so too do free ions such as Mg 2+.
Then, when the cell entered the next mitosis and its chromosomes took on a condensed appearance, the marked regions were analyzed by radiography. Since its inception, the FISH technique has become ...
A protein complex called condensins is involved in assembling the condensed chromosomes. However, researchers are still unsure how cells achieve chromosome assembly during cell division.
reveals a highly organized chromosome consisting of two distinct lobes of condensed inactive DNA with smaller structured domains of active DNA embedded in them. These smaller domains, referred to as ...
They then generated sophisticated computer simulations to match that data, allowing them to calculate the three-dimensional path the chromosomes traced as they condensed. Their models determined ...