An example of a balanced structural change is the Philadelphia chromosome translocation previously described. In that case, although genetic information was rearranged into an abnormal gene ...

What are chromosomal abnormalities? Learn how and why they can result in miscarriage or chromosomal disorders. Finding out you're pregnant should be an exciting time, but it can also be stressful.

Microarray analysis identifies more chromosome abnormalities than traditional karyotyping in prenatal testing. Microarrays will also identify findings of unclear clinical significance that should ...

Aneuploidy and its consequences on the cell Aneuploidy, a state where cells have an incorrect number of chromosomes, is observed in 90% of solid tumors. It results from errors in the segregation ...

2013;13(6):601-611. In other situations, normal microarray analysis in the presence of an abnormal karyotype, such as marker chromosomes, is reassuring, as it indicates that the marker is lacking ...