Antimetabolite infusion is continued until ... Local toxicity without systemic toxicity is the aim of infusion chemotherapy and reflects the development of a local antimetabolic effect.

A concerning relationship between cancer chemotherapy and adverse neurological ... agents—and cytosine arabinoside (cytarabine; an antimetabolite) were distinctly toxic to normal neural ...

The benzimidazole ring, which replaces the benzene ring present in chlorambucil, might be associated with antimetabolite-like activity, but this has not yet been confirmed. The addition of a ...