two factors that contribute to myosin II activity and intracellular tension. Cells on rigid surfaces coated with high densities of ECM proteins exhibit large, myosin II-dependent focal adhesions ...

The Fowler lab discovered that myosin (green) can bind actin (orange) to exert tension on the red blood cell membrane. This tension supports the function of red blood cells by maintaining their ...

Myosin II plays the most important role in cellular force generation. Myosin II molecules self-assemble into filaments with different structures depending on myosin II isoforms and other conditions ...

Cardiac muscle cells appear striated or striped under a microscope. These stripes occur due to alternating filaments that comprise myosin and actin proteins. The dark stripes indicate thick ...