By understanding this "crosstalk" researchers expect to gain insights into autoimmune diseases such as multiple ... describes how cell surface receptors cooperate to generate immune responses ...

Based on meta-analysis of over 100 studies of transmembrane cell-surface receptors ... Therefore, there are many different kinds of receptors. For example, humans have over a thousand encoded ...

To date, about 70 different Rab proteins have ... proteins can lead to a wide range of diseases, and receptors that never reach the cells surface can do the same. While Wu suspects the vesicles ...

Apparently, evolution has assured that ATP is indispensable inside cells, and as a signalling molecule between them. Figure 1: ATP signalling and families of mammalian ionotropic receptors.

1 Cell signaling receptors are proteins on the cell surface or inside the ... neurodegenerative disorders, and autoimmune diseases. There are different causes of signaling dysregulation.

At Tau2020, a new conference held February 12 and13 in Washington, D.C., Ken Kosik, University of California, Santa Barbara, reported that tau slips into cultured human neurons by binding LDL-receptor ...

Local immune effector cell–associated toxicity syndrome is a newly identified side effect observed in many patients receiving CD19-targeting CAR T-cell therapy for autoimmune conditions.

It also could lead to new, targeted therapies for other diseases ... known as synNotch receptors, that could be inserted into cells to reprogram their behavior in response to stimuli. Roybal and ...

Problems with aGPCRs can also lead to diseases like cancer ... that the GAIN domain of the receptor assumed several different positions in relation to the cell surface. Each different position ...

It also could lead to new, targeted therapies for other diseases. The breakthrough, described in Nature, revolves around engineered receptors on the surface ... one cell could affect different ...