During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo. The cells ...

During animal development, cells divide and arrange themselves in a coordinated way, eventually forming the embryo.

T cells play an essential role defending the body against viruses and bacteria. To mount these defenses, T cells must sense these pathogens via cell surface receptors known as antigen receptors.

Activation of transmembrane cell-surface receptors via a common mechanism? The “rotation model” . BioEssays , 2015; 37 (9): 959 DOI: 10.1002/bies.201500041 ...

The UAB researchers showed that TREM2 — which stands for triggering receptors expressed on myeloid cells 2 — is predominantly ...

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M yeloid cells such as monocytes, macrophages, and neutrophils are critical mediators and regulators of immune responses. 1 Derived from hematopoietic stem cells found in the bone marrow, these cells ...

These antigen receptors are complex molecular machines that, when activated, interact with other molecules to initiate a signaling cascade, leading to the differentiation of B cells into plasma ...

T cells play an essential role defending the body against viruses and bacteria. To mount these defenses, T cells must sense these pathogens via cell surface receptors known as antigen receptors.

TREM2, a cell surface receptor on monocyte-derived alveolar macrophages (Mo-AMs), is highly expressed in fibrotic lungs and promotes macrophage survival and lung fibrosis by delaying apoptosis.