The growing problem of antibiotic resistance has ... of proteins that are localized in the bacterial membrane. But where will the cell-division inhibitors come from? There is increasing evidence ...

Antibiotic resistance is a growing ... it could be an Achilles heel in the bacterial shield — inhibitors that access BamA would not need to penetrate the cell. Indeed, a proof-of-concept study ...

The primary reason is that the inhibitors are unable to permeate through the bacterial membrane ... cell more effectively," says Dr. Hou. "Then, combining these inhibitors with traditional ...

Some antibiotics, including tetracycline, which is used to treat acne, respiratory tract infections and other conditions, inhibit protein ... of a bacterium's cell membrane, which controls how ...

Whakaihu Waka researchers have been part of two studies in the battle against drug resistant strains of Mycobacterium ...

Swiss pharmaceutical company Roche has announced that a new antibiotic, zosurabalpin, is progressing to phase 3 testing.

Whether bacteria are resistant to antibiotics is often decided at the cell membrane ... cytotoxins and inhibitors, shed light on how this transport process occurs at the membrane, how it is ...

To fight this resistance, researchers are creating pharmaceuticals that attack and inhibit the ... cost of creating the antibiotic-degrading enzyme has left the resistant cell population depleted ...

unlike most antibiotics. On one hand, they bind to membrane lipids, destabilizing the bacterial membrane. Additionally, they inhibit two enzymes involved in cell wall and protein synthesis.

The drug works differently from currently available antibiotics ... developed drug uses a different tactic. It inhibits a key enzyme in the cell membrane that helps the bacteria secrete proteins.

University of Otago – Ōtākou Whakaihu Waka researchers have been part of two groundbreaking studies in the battle against ...