Whakaihu Waka researchers have been part of two studies in the battle against drug resistant strains of Mycobacterium ...

The growing problem of antibiotic resistance has ... of proteins that are localized in the bacterial membrane. But where will the cell-division inhibitors come from? There is increasing evidence ...

University of Otago – Ōtākou Whakaihu Waka researchers have been part of two groundbreaking studies in the battle against ...

Whether bacteria are resistant to antibiotics is often decided at the cell membrane ... cytotoxins and inhibitors, shed light on how this transport process occurs at the membrane, how it is ...

Swiss pharmaceutical company Roche has announced that a new antibiotic, zosurabalpin, is progressing to phase 3 testing.

The primary reason is that the inhibitors are unable to permeate through the bacterial membrane ... cell more effectively," says Dr. Hou. "Then, combining these inhibitors with traditional ...

unlike most antibiotics. On one hand, they bind to membrane lipids, destabilizing the bacterial membrane. Additionally, they inhibit two enzymes involved in cell wall and protein synthesis.

Some antibiotics, including tetracycline, which is used to treat acne, respiratory tract infections and other conditions, inhibit protein ... of a bacterium's cell membrane, which controls how ...

To fight this resistance, researchers are creating pharmaceuticals that attack and inhibit the ... cost of creating the antibiotic-degrading enzyme has left the resistant cell population depleted ...

Such drugs use mechanisms such as targeting the plasma membrane or cell wall synthesis to disrupt ... IV lipoglycopeptide antibiotic that inhibits bacterial cell wall biosynthesis by binding to the ...

For example, structures called "efflux pumps" in the cell membrane allow bacterial cells to pump out antibiotics that get inside the cell. Bacterial cells can also make enzymes that chemically ...