Carvedilol and metoprolol are both beta-blocker medications, which are a class of drugs used to treat various cardiovascular conditions like heart failure and hypertension (high blood pressure).

The COMET trial included 3029 subjects with NYHA class II-IV heart failure (left ventricular ejection fraction less than or equal to 35%) who were randomly assigned to receive either carvedilol ...

[70] recently reported on switching between β blockers (metoprolol and carvedilol) in 68 patients treated with either agent for 1 year who had improved in terms of LVEF and NYHA class. Patients ...