Using mass spectroscopy–based proteomics, we detected 117 proteins in human vitreous and elevated levels of extracellular carbonic anhydrase ... into the factors and mechanisms responsible ...

Using a method developed by the authors, they were able to identify active carbonic anhydrase in the narrower ... such as Alzheimer's disease. This mechanism elegantly explains how spider silk ...

CARBONIC anhydrase is a zinc metalloenzyme that reversibly catalyzes the hydration of carbon dioxide to bicarbonate and hydrogen ions according to the following equation 1: Blood was obtained from ...

How does acetazolamide work (mechanism of action)? Acetazolamide blocks an enzyme called carbonic anhydrase in the body. This helps lower pressure inside the eye, increases how much you pee to ...

Some of the mechanisms of the different diuretics are described below: These drugs inhibit the enzyme carbonic anhydrase, which has the effect of decreasing the reabsorption of bicarbonate in the ...

This may result from loss of sensitivity to the inhibitory effect of the drug by the carbonic anhydrase system or from local tubular or general metabolic adjustments. If the drug is given only ...

The researchers identified carbonic anhydrase inhibitors as a promising option for reducing tau toxicity. Tauopathies are a group of neurodegenerative diseases caused by the accumulation of tau ...

Carbonic Anhydrase IX Expression, a Novel Surrogate Marker of Tumor Hypoxia, Is Associated With a Poor Prognosis in Non–Small-Cell Lung Cancer. JCO 21 , 473-482 (2003). DOI: 10.1200/JCO.2003.11.132 ...

(d) CAIX staining is diffuse and strong in the tumor cells (40×). CAIX, carbonic anhydrase IX; CK5/6, cytokeratin 5/6. Mesothelioma is an aggressive tumor with a poor prognosis. Histological ...